FADD Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FADD |
| Clone | [5E8-A7] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Entrez Summary: The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals.Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors.Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade.Knockout studies in mice also suggest the importance of this protein in early T cell development.[provided by RefSeq, Jul 2008] |
| Immunogen | Immunogen: Recombinant human FADD protein. Sensitivity: This antibody detects endogenous levels of FADD and does not cross-react with related proteins. Sequence Similarities: Contains 1 death domain.Contains 1 DED (death effector) domain. |
| Other Names | [FADD; FADD protein; FADD_HUMAN; Fas (TNFRSF6) associated via death domain; Fas associated via death domain; Fas associating death domain containing protein; Fas associating death domain containing protein; Fas associating protein; Fas associating protein with death domain; Fas associating protein with death domain; Fas TNFRSF6 associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; FasTNFRSF6 associated via death domain; FasTNFRSF6 associated via death domain; GIG 3; GIG3; Growth inhibiting gene 3 protein; Growth-inhibiting gene 3 protein; H sapiens mRNA for mediator of receptor induced toxicity; H sapiens mRNA for mediator of receptor induced toxicity; Mediator of receptor induced toxicity; Mediator of receptor induced toxicity; MGC8528; MGC8528; MORT 1; MORT1; MORT1; Protein FADD], [GIG3; MORT1.] |
| Gene, Accession # | [FADD], Gene ID: 8772, NCBI: NP_003815.1, UniProt: Q13158 |
| Catalog # | MBS475296 |
| Price | $335 |
| Order / More Info | FADD Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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