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Antigenic Specificity | BCMA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a synthetic peptide mapping at the carboxy terminus of human BCMA. |
Other Names | [tumor necrosis factor receptor superfamily member 17; Tumor necrosis factor receptor superfamily member 17; tumor necrosis factor receptor superfamily member 17; tumor necrosis factor receptor superfamily, member 17; B-cell maturation protein; CD_antigen: CD269] |
Gene, Accession # | [BCMA], Gene ID: 608, NCBI: NP_001183 |
Catalog # | MBS9404019 |
Price | $320 |
Order / More Info | BCMA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |