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Antigenic Specificity | Phospho-Calnexin(Ser564) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Calnexin(Ser564) antibody detects endogenous levels of Calnexin. Function: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.Subunit Structure: Interacts with MAPK3/ERK1 (By similari |
Immunogen | Immunogen: A synthesized peptide derived from human Calnexin around the phosphorylation site of Ser564. Subcellular Location: Endoplasmic Reticulum Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (83%), Horse (83%), Sheep (92%), Rabbit (100%), Dog (83%) |
Other Names | [Calnexin; CALX_HUMAN; CANX; CNX; FLJ26570; Histocompatibility complex class I antigen binding protein p88; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90] |
Gene, Accession # | [CANX], Gene ID: 821, NCBI: NP_001019820.1, UniProt: P27824 |
Catalog # | MBS9600766 |
Price | $240, $280 |
Order / More Info | Phospho-Calnexin(Ser564) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |