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Antigenic Specificity | TRPV3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TRPV3 antibody detects endogenous levels of total TRPV3. Function: Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen).Subunit Structure: May form a heteromeric channel with TRPV1. Interacts with TRPV1.Similarity: Belongs to the transient receptor (TC 1.A.4) fami |
Immunogen | Immunogen: A synthesized peptide derived from human TRPV3 Subcellular Location: Membrane. Tissue Specificity: Abundantly expressed in CNS. Widely expressed at low levels. Detected in dorsal root ganglion (at protein level). Expressed in the keratinocyte layers of the outer root sheath and, to lesser extent, to the matrix of the hair follicles (at protein level). Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep |
Other Names | [transient receptor potential cation channel subfamily V member 3 isoform 2; Transient receptor potential cation channel subfamily V member 3; transient receptor potential cation channel subfamily V member 3; transient receptor potential cation channel subfamily V member 3; Vanilloid receptor-like 3; VRL-3] |
Gene, Accession # | [TRPV3], Gene ID: 162514, NCBI: NP_659505.1, UniProt: Q8NET8 |
Catalog # | MBS9603044 |
Price | $240, $280 |
Order / More Info | TRPV3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |