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Antigenic Specificity | GJA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GJA1 antibody detects endogenous levels of total GJA1. Description: Connexin 43 (Cx43) is a member of the large family of gap junction proteins. Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels. Clusters of these channels assemble to make gap junctions. Gap junction communication is important in development and regulation of cell growth. Phosphorylation of Cx43 is important in regulating assembly and function of gap junctions (1, 2). Ser368 of Cx43 is phosphorylated by protein kinase C (PKC) after activation by phorbol esters, which decreases cell-to-cell communication (3). Src can interact with |
Immunogen | Immunogen: A synthesized peptide derived from human GJA1 Subcellular Location: Cell Membrane. Cell Junction > Gap Junction. Tissue Specificity: Expressed in the heart and fetal cochlea. |
Other Names | [Connexin 43; Connexin-43; Cx 43; Cx43; CXA1_HUMAN; DFNB38; Gap junction 43 kDa heart protein; Gap junction alpha-1 protein; Gap junction protein alpha 1 43kDa (connexin 43); Gap junction protein alpha 1 43kDa; Gap junction protein alpha like; GJA 1; Gja1; GJAL; ODD; ODDD; ODOD; SDTY3] |
Gene, Accession # | [GJA1], Gene ID: 2697, NCBI: NP_000156.1, UniProt: P17302 |
Catalog # | MBS9607539 |
Price | $240, $280 |
Order / More Info | GJA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |