GRP78 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGRP78
Clone[1H11-1H7]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, bovine, Fungi, hamster, monkey, rabbit, Xenopus
IsotypeIgG2b
FormatAPC-Cy7 conjugate
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionDetects ~78 kDa. GRP78 is a ubiquitously expressed, 78-kDa glucose-regulated protein, and is commonly referred to as an immunoglobin chain binding protein (BiP). The BiP proteins are categorized as stress response proteins because they play an important role in the proper folding and assembly of nascent protein and in the scavenging of misfolded proteins in the endoplasmic reticulum lumen. Translation of BiP is directed by an internal ribosomal entry site (IRES) in the 5' non-translated region of the BiP mRNA. BiP IRES activity increases when cells are heat stressed (1). GRP78 is also critical for maintenance of cell homeostasis and the prevention of apoptosis (2). Lou et al. have provided findings that suggest GRP78 is essential for embryo
ImmunogenImmunogen: His-tagged human GRP78
Other Names[Mouse Human GRP78 IgG2b; GRP78 : APC/Cy7; 78 kDa glucose regulated protein; 78 kDa glucose-regulated protein; AL022860; AU019543; BIP; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Endoplasmic reticulum lumenal; Ca2+ binding protein grp78; FLJ26106; Glucose Regulated Protein 78kDa; GRP 78; GRP-78; GRP78_HUMAN; Heat shock 70 kDa protein 5; Heat Shock 70kDa Protein 5; HSCe70; HSPA 5; HSPA5; Immunoglobulin Heavy Chain Binding Protein; Immunoglobulin heavy chain-binding protein; mBiP; MIF2; Sez7]
Gene, Accession #[GRP78], Gene ID: 14828, NCBI: P20029.3, UniProt: P20029
Catalog #MBS8002548
Price$485
Order / More InfoGRP78 Antibody from MYBIOSOURCE INC.
Product Specific References1. Cho S., et al. (2007) Mol Cell Biol. 27(1): 368-83. 2. Yang Y., et al. (1998) J Biol Chem 273: 25552-25555. 3. Luo S., et al (2006) 26 (15): 5688-97. 4. Yu Z., et al. (1999) Exp Neurol. 15: 302-314. 5. Koomagi R., et al. (1999) Anticancer Res. 19:4333-4336. 6. Laquerre S., et al. (1998) J. Virology 72: 4940-4949. 7. Dong D., et al. (2005) Cancer Res 65(13): 5785-91.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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