Edit |   |
---|---|
Antigenic Specificity | FAIM3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | May play a role in the immune system processes. Protects cells from FAS-, TNF alpha-and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-251 of human FAIM3 (NP 005440.1). |
Other Names | [TOSO; FAIM3; FCMR] |
Gene, Accession # | [FAIM3], NCBI: O60667.1, UniProt: O60667 |
Catalog # | MBS8546019 |
Price | $280 |
Order / More Info | FAIM3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |