Estrogen Receptor Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Estrogen Receptor |
| Clone | [AER314] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoprecipitation (IP), ELISA (EIA), Immunohistochemistry (IHC) Frozen/Paraffin, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The human estrogen receptor has a molecular weight of 67 kDa and consists of 6 functional domains (domains A-F). Functional mapping of the estrogen receptor has determined a transcriptional promoting activity in the A/B domain. The hormone-binding domain (E domain) is located towards the carboxy terminal, whereas the DNA-binding domain (C domain) is found in the central portion of the molecule. It has been speculated that the presence in breast cancer cells of truncated forms of the estrogen receptor lacking the hormone-binding domain might promote the uncontrolled growth of the tumor. |
| Immunogen | Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with purified estrogen receptors from calf uterus tumor and mouse myeloma cells. |
| Other Names | [estrogen receptor; Estrogen receptor; estrogen receptor; ER; estradiol receptor; nuclear receptor subfamily 3 group A member 1; estrogen receptor 1 (alpha); ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1], [Esr1; Esr1; ERa; ESR; Estr; ER[a]; Estra; Nr3a1; ERalpha; AA420328; AU041214; ER-alpha; Esr; Estr; Estra; Nr3a1; ER] |
| Gene, Accession # | Gene ID: 13982, NCBI: NP_031982.1, UniProt: P19785 |
| Catalog # | MBS395255 |
| Price | $340 |
| Order / More Info | Estrogen Receptor Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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