chk 1 kinase Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-chk 1 kinase antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | chk 1 kinase |
| Clone | polyclonal |
| Host Species | Sheep |
| Reactive Species | human, mouse, rat, monkey |
| Isotype | n/a |
| Format | ammonium sulfate precipitate |
| Size | 0.25 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The immunogen for anti-human chk-1 was a protein corresponding to amino acid sequence 1-474 and having a molecular weight of 54 kD. One mechanism by which checkpoints maintain the fidelity of cell cycle events is through blocking mitosis in response to unreplicated or damaged DNA. In most species this occurs through inhibiting activation of the cyclic-dependent kinase cdc2, which regulates entry in to mitosis. Chk1, a kinase involved in the DNA damage checkpoint response can phosphorylate Cdc25C an activator of cdc2. It is hypothesized that chk 1 induces serine 216 phosphorylation of Cdc 25C and subsequent binding negatively regulated Cdc25C, thus preventing it from activating cdc2. |
| Immunogen | Immunogen: A GST fusion protein corresponding to amino acid sequence 1-474 and having a molecular weight of 54 kD |
| Other Names | [sheep human chk 1 kinase; checkpoint kinase 1], [CHEK1; CHEK1; CHK1; CHK1] |
| Gene, Accession # | Gene ID: 1111, NCBI: NP_001107593.1, UniProt: O14757 |
| Catalog # | MBS395671 |
| Price | $340 |
| Order / More Info | chk 1 kinase Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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