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Antigenic Specificity | B23 (Phospho Thr234) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-B23 (T234) Polyclonal Antibody detects endogenous levels of B23 protein only when phosphorylated at T234. NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthesized peptide derived from human B23 around the phosphorylation site of T234 |
Other Names | [Rabbit B23 (phospho Thr234); NPM1; NPM; Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin] |
Gene, Accession # | [B23], Gene ID: 4869, NCBI: NP_001032827.1, UniProt: P06748 |
Catalog # | MBS9706045 |
Price | $130, $220, $325 |
Order / More Info | B23 (Phospho Thr234) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |