Edit |   |
Antigenic Specificity | Arpc1b/p41-Arc (Thr-21), Phospho-Specific |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse, chicken, frog |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was affinity purified using phospho-Arpc1b (Thr-21) peptide (without carrier). The antibody detects a 41 kDa* protein corresponding to the molecular mass of Arpc1b on SDS-PAGE immunoblots of human A431 and mouse C2C12 treated with calyculin A. This reactivity is removed with lambda phosphatase treatment. Cellular morphology, adhesion, and motility occur through dynamic reorganization of actin-based superstructures. Actin-binding proteins are critical for regulating actin polymerization and superstructure formation. The Arp2/3 complex is an actin polymerization-inducing complex that includes Arp2, Arp3, p41-Arc, p34-Arc, p21-Arc, p20-Arc, and p16-Arc. Several nucleation promoting factors, such as WASP and coronin, regulate the |
Immunogen | Immunogen: Phospho-Arpc1b/p41-Arc (Thr-21) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding threonine 21 in human Arpc1b. This peptide sequence is highly conserved in rat, mouse, chicken, and fish Arpc1b, and has some homology to the conserved site in isoform Arpc1a. |
Other Names | [Arc41; p41; Arpc1b], [ARPC1B; ARPC1B; ARC41; PLTEID; p40-ARC; p41-ARC; ARC41] |
Gene, Accession # | [Arpc1b/p41-Arc], Gene ID: 10095, NCBI: NP_005711.1, UniProt: O15143 |
Catalog # | MBS474084 |
Price | $385 |
Order / More Info | Arpc1b/p41-Arc (Thr-21), Phospho-Specific Antibody from MYBIOSOURCE INC. |
Product Specific References | Kim, Y.B. et al. (2015) J Biol Chem. 290(34):21076 WB: PC3 cellsHo, H. et al. (2013) Pigment Cell Melanoma Res 26(2):218. Welch, M.D. et al. (1997) J Cell Biol. 138(2):375.Vadlamudi, R.K. et al. (2004) EMBO Rep. 5(2):154.Molli, P.R. et al. (2010) J Cell Biol. 190(1):101. |