Edit |   |
---|---|
Antigenic Specificity | PAX2 (Center), 187-216 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.3 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PAX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human PAX2. PAX2 encodes paired box gene 2, one of many humanhomologues of the Drosophila melanogaster gene prd. The centralfeature of this transcription factor gene family is the conservedDNA-binding paired box domain. PAX2 is believed to be a target oftranscriptional supression by the tumor supressor gene WT1.Mutations within PAX2 have been shown to result in optic nervecolobomas and renal hypoplasia. Alternative splicing of this generesults in multiple transcript variants. |
Immunogen | n/a |
Other Names | [Paired box protein Pax-2; PAX2] |
Gene, Accession # | [PAX2], Gene ID: 5076, NCBI: NP_000269.2, UniProt: Q02962 |
Catalog # | MBS9202941 |
Price | $165, $370 |
Order / More Info | PAX2 (Center), 187-216 Antibody from MYBIOSOURCE INC. |
Product Specific References | Monte, N.M., et al. Cancer Res. 70(15):6225-6232(2010) Ozcan, A., et al. Arch. Pathol. Lab. Med. 134(8):1121-1129(2010) Quick, C.M., et al. Hum. Pathol. 41(8):1145-1149(2010) Martinovic-Bouriel, J., et al. Am. J. Med. Genet. A 152A (4), 830-835 (2010) : Rabban, J.T., et al. Am. J. Surg. Pathol. 34(2):137-146(2010) |