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Antigenic Specificity | CD25 |
Clone | [4C9] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b |
Format | unconjugated |
Size | 5 Control Slides, 0.1 mL (Concentrate), 3 ml (Prediluted) |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD25 is the alpha chain of the IL-2 receptor. It is a Type I transmembrane protein present on activated T-cells, activated B-cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. It is expressed in most B-cell neoplasms, some Acute Non-lymphocytic Leukemias, and Neuroblastomas. Expression of CD25 is a reliable diagnostic tool for distinguishing neoplastic mast-cell aggregates from reactive proliferations, and has, therefore, recently become a minor criterion for the diagnosis of Systemic Mastocytosis (SM). Anti-CD25 antibodies have also been useful in identifying mast cells in skin biopsies in the setting of Urticaria Pigmentosa, w |
Immunogen | Immunogen: Recombinant protein corresponding to the external domain of the Interleukin-2 Receptor molecule. Precautions: 1. This product contains sodium azide (NaN3), a toxic chemical which may react with plumbing to form highly explosive build-ups of metal azides. Upon disposal, flush with large volumes of water to prevent sodium azide build-up. 2. Ensure proper handling procedures are used with reagent. Always wear proper laboratory equipment such as laboratory coat and gloves when handling re |
Other Names | [CD25; Peripheral myelin protein 22; Protein CD25; SR13 myelin protein; Schwann cell membrane glycoprotein], [Pmp22; Cd25; Pmp-22] |
Gene, Accession # | [CD25], UniProt: P25094 |
Catalog # | MBS370153 |
Price | $130, $220, $250 |
Order / More Info | CD25 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |