PAR2 (Proteinase Activated Receptor 2) (PE) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PAR2 (Proteinase Activated Receptor 2) (PE) |
| Clone | [7H40] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | purified |
| Size | 100 tests |
| Concentration | 0.05 mg/ml |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human PAR2. Human protease-activated receptor 2 (PAR2) is one of 4 members in a unique subclass of the Class A G protein- coupled receptor superfamily. Receptor activation involves the proteolytic uncovering of a cryptic N-terminus receptor sequence that forms a tethered ligand and binds to the receptors within the extracellular loop 2. This activates the receptors to initiate multiple signaling cascades. In addition, short peptides (5-6 amino acids) synthesized based on the proteolytically revealed motif can activate the receptors without the cleavage by enzymes. PAR2 is activated by trypsin and trypsin-like enzymes, and the cleavage site has been identified at residue Arg 36. PAR2 plays an important role in the regulation of ca |
| Immunogen | Immunogen: NS0 mouse myeloma cell line transfected with human PAR2, Accession # P55085 |
| Other Names | [-PAR2 (Proteinase Activated Receptor 2) (PE)], [F2RL1; F2RL1; PAR2; GPR11; GPR11; PAR2] |
| Gene, Accession # | Gene ID: 2150, NCBI: NP_005233.3, UniProt: P55085 |
| Catalog # | MBS601417 |
| Price | $685 |
| Order / More Info | PAR2 (Proteinase Activated Receptor 2) (PE) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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