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Antigenic Specificity | ATG5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents (1, 2). Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer (3). The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles (4-6). This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10 (7, 8). |
Immunogen | Immunogen: Recombinant protein of human ATG5 Observed Molecular Weight: 32kDa |
Other Names | [ATG5; APG5; APG5-LIKE; APG5L; ASP; hAPG5] |
Gene, Accession # | [ATG5], Gene ID: 9474, NCBI: AGC52703.1 |
Catalog # | MBS2517655 |
Price | $150, $225, $360 |
Order / More Info | ATG5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |