XAF-1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-XAF-1 antibody, protein, ELISA kits.
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| Antigenic Specificity | XAF-1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | XAF-1 Antibody: XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and -9, and triggers its relocation from the cytosol to the nucleus. Overexpression of XAF-1 results in the neutralization of XIAP's ability to inhibit cell death. XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines. In contrast, XIAP levels have been shown to be high in a majority of cell lines. Low XAF-1 and high basal expression of XIAP may therefore play a critical role in maintaining survival of cancer cell lines. Both IFN-alpha2 and IFN-beta can induce XAF-1 mRNA in all cells examined but induction of XAF-1 protein (as observed by immunoblot analysis) was seen only in cell lines s |
| Immunogen | Immunogen: XAF-1 antibody was raised against a synthetic peptide corresponding to 16 amino acids near the middle of human XAF-1. Buffer: XAF-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [XAF-1; BIRC4BP; XIAPAF1; HSXIAPAF1; BIRC4BP; XIAP-associated factor 1; BIRC4-binding protein; XIAP associated factor 1], [XAF1; XAF1; BIRC4BP; XIAPAF1; HSXIAPAF1; BIRC4BP; XIAPAF1] |
| Gene, Accession # | [XAF1], Gene ID: 54739, NCBI: CAA68030, UniProt: Q6GPH4 |
| Catalog # | MBS150787 |
| Price | $375 |
| Order / More Info | XAF-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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