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Antigenic Specificity | SIRT4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Silent information regulator (Sir2)-like family deacetylases (also known as sirtuins) are highly conserved proteins and have important roles in the regulation of metabolism, inflammation, cellular survival growth and differentiation. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD-dependent protein ADP-ribosyl transferase which catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase (GLUD1), and may involve in the regulation of insulin secretion. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 72 of rat SIRT4. Positive Control: Rat kidney tissue lysate |
Other Names | [NAD-dependent deacetylase sirtuin-4; SIR2-like protein 4], [Sirt4] |
Gene, Accession # | [SIRT4], UniProt: B2RZ30 |
Catalog # | MBS841293 |
Price | $150, $300 |
Order / More Info | SIRT4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |