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Antigenic Specificity | INPP5B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: bovine, sheep |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: INPP5B Antibody detects endogenous levels of INPP5B. Description: Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events.Post Translational Modifications: Isoprenylation at Cys-990 may be required for localization at the membrane. May be proteolytically cleaved after Lys-320 as inferred from N-terminal protein sequence of the 75 kda form.Subunit Structure: Interacts with APPL1, FAM109A and FAM109B. Interacts with several Rab GTPases, at least RAB1A, RAB2A, RAB5A, RAB6A, RAB8A, RAB9A and RAB33B; these interactions may play a dual role in targeting INPP5B to the specific me |
Immunogen | Immunogen: A synthesized peptide derived from human INPP5B. Tissue Specificity: Platelets. |
Other Names | [4; 5-trisphosphate 5-phosphatase; 5PTase; 75 kDa inositol polyphosphate 5 phosphatase; 75 kDa inositol polyphosphate-5-phosphatase; 75kDa; EC 3.1.3.36; I5P2_HUMAN; Inositol polyphosphate 5-phosphatase II; Inositol polyphosphate-5-phosphatase B; Inositol polyphosphate-5-phosphatase, 75kDa; INPP5B; Inpp5b protein; INPP5P; MGC65156; MGC71303; OTTHUMP00000004726; OTTHUMP00000004727; OTTHUMP00000004728; Phosphoinositide 5 phosphatase; Phosphoinositide 5-phosphatase; Type II inositol 1,4,5 trisphosphate 5 phosphatase; Type II inositol-1] |
Gene, Accession # | [INPP5B], Gene ID: 3633, NCBI: NP_005531.2, UniProt: P32019 |
Catalog # | MBS9611840 |
Price | $240, $280 |
Order / More Info | INPP5B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |