Human Interferon regulatory factor 8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Interferon regulatory factor 8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes. |
| Immunogen | Immunogen: Recombinant human Interferon regulatory factor 8 protein (137-426aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-79535 / sc-79536 / sc-6058 / sc-13043 |
| Other Names | [IRF-8; Interferon consensus sequence-binding protein; H-ICSBP; ICSBP; IRF8; ICSBP1], [IRF8; IRF8; ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP; ICSBP1; IRF-8; H-ICSBP; ICSBP] |
| Gene, Accession # | [IRF8], Gene ID: 3394, NCBI: NP_002154.1, UniProt: Q02556 |
| Catalog # | MBS1496444 |
| Price | $120, $160 |
| Order / More Info | Human Interferon regulatory factor 8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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