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Antigenic Specificity | VCAM1/Cd106 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
Immunogen | Immunogen: A synthesized peptide derived from human VCAM1. Subcellular Localization: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue. |
Other Names | [Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; INCAM-100; CD106; VCAM1; L1CAM], [VCAM1; VCAM1; CD106; INCAM-100; V-CAM 1; VCAM-1] |
Gene, Accession # | [VCAM1], Gene ID: 7412, NCBI: NP_001069.1, UniProt: P19320 |
Catalog # | MBS179587 |
Price | $160, $340, $340 |
Order / More Info | VCAM1/Cd106 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |