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Antigenic Specificity | ABC3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of ABC3A protein. APOBEC3A (Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3A) is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by APOBEC3A lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which lea |
Immunogen | Immunogen: Synthesized peptide derived from part region of human ABC3A protein at amino acid sequence of 80-160 |
Other Names | [Rabbit ABC3A; DNA dC->dU-editing enzyme APOBEC-3A; A3A; Phorbolin-1] |
Gene, Accession # | [ABC3A], Gene ID: 200315, NCBI: NP_001180218.1, UniProt: P31941 |
Catalog # | MBS9708247 |
Price | $130, $220, $325 |
Order / More Info | ABC3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |