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Antigenic Specificity | HtrA2 |
Clone | [AT3F9] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 kappa |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HtrA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP)-binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death. |
Immunogen | Immunogen: HtrA2 antibody was raised in Mouse using recombinant human HtrA2 (134-458aa) purified from E Coli as the immunogen |
Other Names | [Mouse HtrA2; HtrA2; HtrA2; HTRA2; OMI; PRSS25; HtrA2/Omi; EC 3.4.21.108; High temperature requirement protein A2; HtrA2; Omi stress-regulated endoprotease; Serine proteinase OMI; Serine protease 25; Serine protease HTRA2; mitochondrial; High temperature requirement protein A2] |
Gene, Accession # | [HtrA2], NCBI: JAO26623.1 |
Catalog # | MBS5310739 |
Price | $375 |
Order / More Info | HtrA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |