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Antigenic Specificity | ECRG4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ECRG4 antibody is predicted to not cross-react with other ECRG family members. The esophageal cancer-related gene 4 (ECRG4), also known as Augurin, was identified through differential display screening between esophageal cancer and normal tissue. Hypermethylation of CpG sites in the ECRG4 promoter correlate with ECRG4 downregulation in numerous esophageal squamous cell carcinoma tissues. In transfected cells, overexpression of ECRG4 induced G1 arrest, dephosphorylation of Rb and decreased expression of cyclins D1 and D3. Increased expression of ECRG4 in aged mouse brain is observed compared with young mouse brain. The increased ECRG4 level was accompanied by elevated senescence-associated acidic beta-galactosidase activity, sug |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 20 amino acid peptide near the carboxy terminus of human ECRG4. |
Other Names | [Esophageal cancer-related gene 4 protein, Augurin, C2orf40] |
Gene, Accession # | [ECRG4], Gene ID: 84651, NCBI: AAI09386 |
Catalog # | MBS9408781 |
Price | $320 |
Order / More Info | ECRG4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |