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Antigenic Specificity | Human INSULIN-LIKE GROWTH FACTOR II |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | ELISA (EIA), Functional Assays (FN), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human Insulin-Like Growth Factor II antibody recognizes human IGF-II (Insulin-like Growth Factor II), a 67 amino acid mitogenic polypeptide and member of the Insulin gene family, synthesized by various foetal tissues during prenatal development, under the influence of placental lactogen. IGF-II is a growth factor which exhibits both paracrine and autocrine properties and signals by binding to the type 1 and type 2 insulin-like growth factor receptors (type 1 IGFR and type 2 IGFR), and also to the insulin receptor (IR). The availability of IGF-II is dependent upon its attachment to, and release from, various IGF binding proteins (IGFBPs), a relationship which has been investigated in breast cancer research (Singer et al. 2004). |
Immunogen | Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human IGF-II were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [insulin-like growth factor II isoform 1 preproprotein; Insulin-like growth factor II; insulin-like growth factor II; T3M-11-derived growth factor; insulin-like growth factor 2 (somatomedin A); insulin-like growth factor type 2; insulin-like growth factor 2; Somatomedin-A; T3M-11-derived growth factorCleaved into the following 3 chains:Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin], [IGF2; IGF2; IGF-II; PP9974; C11orf43; IGF-II] |
Gene, Accession # | Gene ID: 3481, NCBI: NP_000603.1, UniProt: P01344 |
Catalog # | MBS221715 |
Price | $550 |
Order / More Info | Human INSULIN-LIKE GROWTH FACTOR II Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |