Edit |   |
---|---|
Antigenic Specificity | CARD11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL1 |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [PPBL; BENTA; BIMP3; IMD11; CARMA1] |
Gene, Accession # | [CARD11], Gene ID: 84433, NCBI: Q9BXL7.3, UniProt: Q9BXL7 |
Catalog # | MBS9127733 |
Price | $200, $275, $430 |
Order / More Info | CARD11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |