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Antigenic Specificity | RAG1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RAG1 antibody detects endogenous levels of total RAG1. Description: The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.Function: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In |
Immunogen | Immunogen: Purified recombinant fragment of human RAG1 expressed in E. Coli Subcellular Location: Nucleus. Tissue Specificity: Maturing lymphoid cells. |
Other Names | [E3 ubiquitin-protein ligase RAG1; RAG-1; RAG1; RAG1_HUMAN; recombination activating gene 1; recombination activating protein 1; RING finger protein 74; RNF74; V(D)J recombination-activating protein 1] |
Gene, Accession # | [RAG1], Gene ID: 5896, NCBI: NP_000439.1, UniProt: P15918 |
Catalog # | MBS9602319 |
Price | $235, $295, $370 |
Order / More Info | RAG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |