URM1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityURM1
Clone[182CT27.2.2]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgM,K
Formatunconjugated
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 1.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis URM1 monoclonal antibody is generated from mouse immunized with URM1 recombinant protein. Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins; the relevance of such function is however unclear in vivo.
Immunogenn/a
Other Names[Ubiquitin-related modifier 1 {ECO:0000255|HAMAP-Rule:MF_03048}; URM1 {ECO:0000255|HAMAP-Rule:MF_03048}; C9orf74]
Gene, Accession #[URM1], Gene ID: 81605, NCBI: NP_001129419.1, UniProt: Q9BTM9
Catalog #MBS9200191
Price$165, $370
Order / More InfoURM1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSchlieker, C.D., et al. Proc. Natl. Acad. Sci. U.S.A. 105(47):18255-18260(2008) Schmitz, J., et al. Biochemistry 47(24):6479-6489(2008) Xu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(31):11625-11630(2006) Singh, S., et al. Protein Sci. 14(8):2095-2102(2005) Humphray, S.J., et al. Nature 429(6990):369-374(2004)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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