Edit |   |
---|---|
Antigenic Specificity | URM1 |
Clone | [182CT27.2.2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM,K |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 1.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This URM1 monoclonal antibody is generated from mouse immunized with URM1 recombinant protein. Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins; the relevance of such function is however unclear in vivo. |
Immunogen | n/a |
Other Names | [Ubiquitin-related modifier 1 {ECO:0000255|HAMAP-Rule:MF_03048}; URM1 {ECO:0000255|HAMAP-Rule:MF_03048}; C9orf74] |
Gene, Accession # | [URM1], Gene ID: 81605, NCBI: NP_001129419.1, UniProt: Q9BTM9 |
Catalog # | MBS9200191 |
Price | $165, $370 |
Order / More Info | URM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Schlieker, C.D., et al. Proc. Natl. Acad. Sci. U.S.A. 105(47):18255-18260(2008) Schmitz, J., et al. Biochemistry 47(24):6479-6489(2008) Xu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(31):11625-11630(2006) Singh, S., et al. Protein Sci. 14(8):2095-2102(2005) Humphray, S.J., et al. Nature 429(6990):369-374(2004) |