Akt2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Akt2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | 1ug/ul |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Akt2 (phospho-Ser474) antibody detects endogenous levels of Akt2 only when phosphorylated at serine 474. This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008] |
| Immunogen | Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Akt2 around the phosphorylation site of serine 474 (Q-F-SP-Y-S). |
| Other Names | [AKT2 protein, partial; RAC-beta serine/threonine-protein kinase; RAC-beta serine/threonine-protein kinase; PKB beta; RAC-PK-beta; murine thymoma viral (v-akt) homolog-2; protein kinase Akt-2; protein kinase B beta; rac protein kinase beta; v-akt murine thymoma viral oncogene homolog 2; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta], [AKT2; AKT2; PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA] |
| Gene, Accession # | [Akt2], Gene ID: 208, NCBI: AAH32709.1 |
| Catalog # | MBS417222 |
| Price | $325 |
| Order / More Info | Akt2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sun M, et al. (2001) Cancer Res; 61(16): 5985-91.Yuan ZQ, et al. (2000) Oncogene; 19(19): 2324-30.Meier R, et al. (1997) J Biol Chem; 272(48): 30491-7. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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