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Antigenic Specificity | Human Trimethylguanosine synthase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation. |
Immunogen | Immunogen: Recombinant human Trimethylguanosine synthase protein(713-853AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23113 / sc-23114 |
Other Names | [CLL-associated antigen KW-2; Cap-specific guanine-N2 methyltransferase; Hepatocellular carcinoma-associated antigen 137; Nuclear receptor coactivator 6-interacting protein; PRIP-interacting protein with methyltransferase motif; PIMT; PIPMT; HCA137; NCOA6IP; PIMT; TGS1], [TGS1; TGS1; PIMT; PIPMT; NCOA6IP; HCA137; NCOA6IP; PIMT; PIMT; PIPMT] |
Gene, Accession # | [TGS1], Gene ID: 96764, NCBI: NP_079107.6, UniProt: Q96RS0 |
Catalog # | MBS969032 |
Price | $160, $235 |
Order / More Info | Human Trimethylguanosine synthase Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |