Bif Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Bif |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Bif Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases. Proteins that comprise the Bcl-2 family such as Bax appear to control the activation of these enzymes. Bax activity was found to be regulated by its association with Bax-interacting factor 1 (BIF), a member of the endophilin B family that is associated with intracellular membranes. Following this interaction, Bax undergoes a conformational change and translocates to mitochondrial membranes. The Bax/BIF interaction appears to be enhanced by apoptotic stimuli, suggesting that BIF acts as the trigger to activate Bax, and as suppression of BIF promoted |
| Immunogen | Immunogen: BIF antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human BIF. Buffer: Bif Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [Bif; Bif-1; CGI-61; PPP1R70; dJ612B15.2; KIAA0491; Endophilin-B1; Bax-interacting factor 1; Bif-1; SH3-domain GRB2-like endophilin B1], [SH3GLB1; SH3GLB1; Bif-1; CGI-61; PPP1R70; dJ612B15.2; KIAA0491; Bif-1] |
| Gene, Accession # | [SH3GLB1], Gene ID: 51100, NCBI: AAK27365, UniProt: Q9Y371 |
| Catalog # | MBS150193 |
| Price | $375 |
| Order / More Info | Bif Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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