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Antigenic Specificity | Cre |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes a 343 amino acid recombinase protein. The Cre (cyclization recombination) enzyme, a member of a large family of recombinases, recognizes loxP which is a sequence motif of 34 bp from the PI bateriophage. If a DNA seqment is flanked by two loxP sites in the same orientation, Cre excises that seqment leaving a single loxP site in the remaining DNA molecule. The excised DNA segment is subsequently degraded. Cre and lox comprise the Cre/lox system which was first developed in the late 1980's to artificially manipulate gene expression (reviewed in Branda and Dymecki, 2004; Ghosh and Duyne, 2002; and Gilbertson, 2003). As an example, mice with the Cre protein expressing in a specific cell type are bred with mice that conta |
Immunogen | Immunogen Information: A synthethic peptide of the bacteriophage protein Cre (amino acids 57-73 KLNNRKWFPAEPEDVRD) was used as immunogen for this antibody |
Other Names | [TOP1; DNA topoisomerase I; to Cre; Cre; Cre], [TOP1; TOP1; TOPI] |
Gene, Accession # | [Cre], Gene ID: 7150, NCBI: P11387.2, UniProt: P11387 |
Catalog # | MBS668606 |
Price | $270 |
Order / More Info | Cre Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |