Human PUMA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman PUMA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunoaffinity purified
Size0.05 mg
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB)
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DescriptionSpecificity: synthetic peptide corresponding to 14 amino acids near the carboxy terminus of human PUMA-a (GenBank Accession number Q9BXH1) This sequence is identical between a and b forms of the PUMA proteins. Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse. PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53.
ImmunogenImmunogen Description: A synthetic peptide corresponding to 14 amino acids near the carboxy terminus of human PUMA-a (GenBank Accession number Q9BXH1) This sequence is identical between a and b forms of the PUMA proteins.
Other Names[PUMA (C-Terminus) IHC-plus; BBC3; Bcl-2-binding component 3; BCL2 binding component 3; JFY-1; JFY1; PUMA; Human PUMA], [BBC3]
Gene, Accession #[PUMA], Gene ID: 27113, NCBI: NP_055232.1, UniProt: Q9BXH1
Catalog #MBS241250
Price$660
Order / More InfoHuman PUMA Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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