Histone H2A.X (Ser139) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Histone H2A.X (Ser139) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from human. Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient |
| Immunogen | n/a |
| Other Names | [Histone H2AX; H2a/x; Histone H2AX; H2AFX; H2AX] |
| Gene, Accession # | [H2AFX], Gene ID: 3014, NCBI: NP_002096.1, UniProt: P16104 |
| Catalog # | MBS9201443 |
| Price | $165, $370 |
| Order / More Info | Histone H2A.X (Ser139) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Mannironi C.,et al.Nucleic Acids Res. 17:9113-9126(1989). Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. Rogakou E.P.,et al.J. Biol. Chem. 273:5858-5868(1998). Rogakou E.P.,et al.J. Cell Biol. 146:905-916(1999). Paull T.T.,et al.Curr. Biol. 10:886-895(2000). |
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MYBIOSOURCE INC.
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