Phospho-CDCP1 (Tyr734) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-CDCP1 (Tyr734) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | humanpredicted: porcine, horse, sheep, rabbit, chicken, Xenopus |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-CDCP1 (Tyr734) Antibody detects endogenous levels of CDCP1 only when phosphorylated at Tyr734. Description: May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.Post Translational Modifications: Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin a |
| Immunogen | Immunogen: A synthesized peptide derived from human CDCP1 around the phosphorylation site of Tyr734. Tissue Specificity: Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal |
| Other Names | [9030022E12Rik; AA409659; CD 318; CD_antigen=CD318; CD318; CD318 antigen; CDCP 1; Cdcp1; CDCP1_HUMAN; CUB domain containing protein 1; CUB domain-containing protein 1; E030027H19Rik; FLJ13772; FLJ22375; FLJ22969; Membrane glycoprotein gp140; MGC31813; OTTHUMP00000164120; OTTHUMP00000209568; RGD1305578; SIMA 135; SIMA135; Subtractive immunization M plus HEp3 associated 135 kDa protein; Subtractive immunization M plus HEp3-associated 135 kDa protein; Transmembrane and associated with src kinases; TRASK] |
| Gene, Accession # | [CDCP1], Gene ID: 64866, NCBI: NP_073753.3, UniProt: Q9H5V8 |
| Catalog # | MBS9610799 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-CDCP1 (Tyr734) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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