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Antigenic Specificity | F11R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840). |
Immunogen | Immunogen: Recombinant Human Junctional adhesion molecule A protein (31-224AA) |
Other Names | [Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321; F11R; JAM1; JCAM; UNQ264/PRO301] |
Gene, Accession # | [F11R], Gene ID: 50848, NCBI: NP_001335020.1, UniProt: Q9Y624 |
Catalog # | MBS7103714 |
Price | $160, $235 |
Order / More Info | F11R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |