ARC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityARC
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionARC Antibody: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK BCL10, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
ImmunogenImmunogen: ARC antibody was raised against a 17 amino acid peptide near the amino terminus of human ARC. Buffer: ARC Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[ARC; ARC; FCM; MYP; NOP; NOP30; ARC; Nucleolar protein 3; Apoptosis repressor with CARD; Myp; nucleolar protein 3 (apoptosis repressor with CARD domain)], [NOL3; NOL3; ARC; FCM; MYP; NOP; NOP30; ARC; NOP; Myp; Nop30]
Gene, Accession #[NOL3], Gene ID: 8996, NCBI: NP_003937, UniProt: O60936
Catalog #MBS150436
Price$375
Order / More InfoARC Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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