Apaf-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityApaf-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, bovine, rabbit, monkey, horse
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.2 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionBackground: During apoptosis, Apaf-1 (apoptosis protease activating factor 1) binds to cytochrome c (Apaf-2), a reaction that requires dATP, and this leads to the formation of a large multimeric complex. The complex recruits pro-caspase-9, and activates caspase-9 (Apaf-3). Activated caspase-9 in turn cleaves and activates caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. Apaf-1 is ubiquitously expressed in human tissues.
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 1161 of human Apaf-1
Other Names[APAF1; CED4; DKFZp781B1145; KIAA0413], [APAF1; APAF1; CED4; APAF-1; KIAA0413; APAF-1]
Gene, Accession #[Apaf-1], Gene ID: 317, NCBI: NP_001151.1, UniProt: O14727
Catalog #MBS840415
Price$305
Order / More InfoApaf-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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