ER-alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityER-alpha
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: ER-alpha antibody detects endogenous levels of total ER-alpha. Description: The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ER mRNA transcripts, which differ primarily in their 5-prime untranslated regions. Two isoforms of the human ER, ERA and ER-beta, occur, each with distinct tissue and cell patterns of expression. Pelletier and El-Alfy (2000) studied the immunocytochemical localization of ESRA and ESRB in human reproductive tissues. In the ovary, ERB immunoreactivity was found in nuclei of granulosa cells of growing follicles at all stages from primary to matu
ImmunogenImmunogen: Purified recombinant fragment of human ER-alpha expressed in E. Coli Subcellular Location: Nucleus. Cytoplasm. Cell Membrane. A minor fraction is associated with the inner membrane and Nucleus. Cytoplasm. Cell Membrane. Associated with the inner membrane via palmitoylation. Tissue Specificity: Widely expressed. Isoform 3 is not expressed in the pituitary gland.
Other Names[DKFZp686N23123; ER alpha; ER; ER-alpha; Era; ESR; ESR1; ESR1_HUMAN; ESRA; Estradiol receptor; Estrogen nuclear receptor alpha; Estrogen receptor 1; Estrogen receptor alpha 3*, 4, 5, 6, 7*/822 isoform; Estrogen receptor alpha; Estrogen receptor alpha delta 3*, 4, 5, 6, 7*, 8*/941 isoform; Estrogen receptor alpha delta 3*, 4, 5, 6, 7*/819 2 isoform; Estrogen receptor alpha delta 4 +49 isoform; Estrogen receptor alpha delta 4*, 5, 6, 7*/654 isoform; Estrogen receptor alpha delta 4*, 5, 6, 7, 8*/901 isoform; Estrogen receptor alpha E1 E2 1 2; Estrogen receptor alpha E1 N2 E2 1 2; Estrogen receptor; ESTRR; NR3A1; Nuclear receptor subfamily 3 group A member 1]
Gene, Accession #[ER-alpha], Gene ID: 2099, NCBI: NP_000116.2, UniProt: P03372
Catalog #MBS9602385
Price$235, $295, $370
Order / More InfoER-alpha Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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