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Antigenic Specificity | Human MAP1LC3A/B (N-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human MAP1LC3A/B (N-Terminal) antibody specifically recognizes an epitope within the N-Terminal (NT) region of both MAP1LC3A (Microtubule-associated proteins 1A/1B light chain 3A/LC3A) and MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B/LC3B), ubiquitin-like proteins and members of the MAP1LC3 family, which are widely used as reliable markers for the monitoring of autophagy. LC3-I is the cytosolic form of LC3, which is converted into the active, membrane-bound form LC3-II, during the autophagy process. Tracking the level of conversion of LC3-I to LC3-II provides an indicator of autophagic activity, and levels of LC3-II in particular, correlate with the extent of autophagosome formation, due to its association with |
Immunogen | Immunogen: Synthetic peptide sequence PSDRPFKQRRSFADC from the N-Terminal region of LC3A (NP 115903.1; NP 852610.1). Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human LC3A was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human |
Other Names | [microtubule-associated proteins 1A/1B light chain 3B; Microtubule-associated proteins 1A/1B light chain 3B; microtubule-associated proteins 1A/1B light chain 3B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; autophagy-related ubiquitin-like modifier LC3 B; microtubule-associated protein 1 light chain 3 beta; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light chain 3 beta], [MAP1LC3B; MAP1LC3B; LC3B; ATG8F; MAP1LC3B-a; MAP1A/1BLC3; MAP1ALC3; MAP1A/MAP1B LC3 B] |
Gene, Accession # | [MAP1LC3A/B], Gene ID: 81631, NCBI: NP_073729.1 |
Catalog # | MBS224211 |
Price | $520 |
Order / More Info | Human MAP1LC3A/B (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |