Phospho-ATM-S1981 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-ATM-S1981
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding S1981 of human ATM Calculated Molecular Weight: 350kDa
Other Names[Phospho-ATM-S1981: AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1], [ATM; ATM; AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1; A-T mutated]
Gene, Accession #[ATM], Gene ID: 472, NCBI: Q13315.4, UniProt: Q13315
Catalog #MBS125807
Price$235, $350, $525
Order / More InfoPhospho-ATM-S1981 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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