WAVE (Tyr-150), phospho-specific [Conserved Site] Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityWAVE (Tyr-150), phospho-specific [Conserved Site]
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA, Western Blot
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DescriptionThis antibody was cross-adsorbed to phospho-WAVE (Tyr-125) and unphosphorylated WAVE (Tyr-150) peptides before affinity purification using phospho-WAVE (Tyr-150) peptide. In western blots, the antibody detects a 78 kDa* corresponding to phosphorylated WAVE2 in K562 cells treated with pervanadate and a 80 kDa band corresponding to WAVE1 in HUVEC treated with pervanadate. It also recognizes an unidentified band near 50 kDa in K562 cells. The Wiskott-Aldrich syndrome protein (WASP) family is involved in various pathways that regulate actin cytoskeletal organization. This family includes WASP, N-WASP, and three WAVE/SCAR isoforms, WAVEs 1, 2, and 3. WAVE proteins play key roles in actin-mediated cell events, such as membrane ruffling and lamell
ImmunogenImmunogen: Phospho-WAVE (Tyr-150) peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr-150 in human WAVE2. This sequence has high homology with similar regions in rat and mouse WAVE2, and has homology to the conserved sites in WAVE1 (Tyr-151) and WAVE3 (Tyr-151).
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS472068
Price$385
Order / More InfoWAVE (Tyr-150), phospho-specific [Conserved Site] Antibody from MYBIOSOURCE INC.
Product Specific References• Ardern, H. et al. (2006) Cell Motil. Cytosk. 63:6.• Leng, Y. et al. (2005) PNAS 102(4):1098.• Suetsugu, S. et al. (1999) Bioch. Biophs. Res. Comm. 260:296.• Miki, H. et al. (1999) J Biol. Chem. 274(39):27605.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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