IDO, Human Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | IDO, Human |
| Clone | polyclonal |
| Host Species | Sheep |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunoassay (IA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The polyclonal antibody recognizes human indoleamine 2,3-dioxygenase (IDO). IDO is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules, like tryptophan, serotonin and melatonin. By doing this, IDO initiates the production of biologically active metabolites, commonly referred to as kynurenines. IDO is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs). In inflammation, interferons (IFNs) act on specific receptors to trigger IDO induction. The production of IFN-gamma and induction of IDO represent important antimicrobial mechanisms. Degradation and depletion of tryptophan by IDO inhibits t |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [IDO] |
| Catalog # | MBS584496 |
| Price | $555 |
| Order / More Info | IDO, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Grohmann, U et al; Tolerance, DCs and tryptophan: much ado about IDO. Trends Immunol 2003, 24: 242 2. Royer, P et al; The Mannose Receptor Mediates the Uptake of Diverse Native Allergens by Dendritic Cells and Determines Allergen-Induced T Cell Polarization through Modulation of IDO Activity. J Immunol 2010, 185:1522 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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