polyprotein (contain Core protein p21)- (N-terminal) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | polyprotein (contain Core protein p21)- (N-terminal) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.1 mg |
| Concentration | 1ug/ul |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Core protein (Core protein p21 (Capsid protein C) (p21) and Core protein p19) packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Core protein modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Core protein also regulates many host cellular functions such as signaling pathways and apoptosis. It prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Core protein is thought to play a role in virus-mediated cell transformation leading to hepatocellular carcinomas. It interacts with, and activates STAT3 leading to cellular transformation. Core prote |
| Immunogen | Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of Hepatitis C virus core protein |
| Other Names | [polyprotein; Genome polyprotein; polyprotein; NIa-Vpg (genome-linked protein); P1 protein (protease); Hc-Pro (Helper component for aphid transmission, protease); P3 protein; 6K1 protein; CI (cytoplasmic inclusion) protein; 6K2 protein; NIa-Pro (Nuclear inclusion protein, protease); NIb (Nuclear inclusion protein, replicase; coat protein], [polyprotein] |
| Gene, Accession # | Gene ID: 932253, NCBI: NP_569138.1 |
| Catalog # | MBS418342 |
| Price | $445 |
| Order / More Info | polyprotein (contain Core protein p21)- (N-terminal) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Cantaloube, J.F., et al, J. Gen. Virol. 84 (Pt 2), 441-446 (2003) Youn, J.W., et al, J. Virol. 77 (21), 11596-11602 (2003) Bukh, J., et al, J. Infect. Dis. 178 (4), 1193-1197 (1998) McLauchlan, J., J. Viral Hepat. 7 (1), 2-14 (2000) Penin, F., et al, Hepatology 39 (1),5-19 (2004) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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