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Antigenic Specificity | Human CD48 |
Clone | [156-4H9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn. |
Immunogen | n/a |
Other Names | [Human CD48; CD48 antigen; Cd48; BCM1 surface antigen; BLAST-1; HM48-1; MRC OX-45 surface antigen; SLAMF2; sgp-60; CD48] |
Gene, Accession # | [CD48], Gene ID: 962, NCBI: NP_001769.2, UniProt: P09326 |
Catalog # | MBS2553845 |
Price | $70, $115 |
Order / More Info | Human CD48 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Fisher RC and Thorley-Lawson DA. 1991. Mol. Cell. Biol. 11:1614. 2. Korinek V, et al. 1991. Immunogenetics 33:108. 3. Leukocyte Typing IV. Knapp W, et al. (Eds) Oxford University Press (1989). 4. Leukocyte Typing V. Schlossman S, et al. (Eds) Oxford University Press (1995). |