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Antigenic Specificity | MEK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous MEK2 protein. The protein encoded by MAP2K2 (mitogen-activated protein kinase kinase 2) is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in MAP2K2 cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involve |
Immunogen | Immunogen: Recombinant Protein of MEK2 |
Other Names | [Rabbit MEK2 Rabbit; Dual specificity mitogen-activated protein kinase kinase 2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2] |
Gene, Accession # | [MEK2], Gene ID: 5605, NCBI: P36507.1, UniProt: P36507 |
Catalog # | MBS9708182 |
Price | $130, $220, $325 |
Order / More Info | MEK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |