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Antigenic Specificity | TIMM8A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.6 mg/mL |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TIMM8A protein. This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Immunogen | Immunogen: Fusion protein of human TIMM8A Immunogen Type: Peptide |
Other Names | [DDP; MTS; DDP1; DFN1; TIM8] |
Gene, Accession # | [TIMM8A], Gene ID: 1678, NCBI: NP_004076.1, UniProt: O60220 |
Catalog # | MBS9430245 |
Price | $255 |
Order / More Info | TIMM8A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |