TBB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTBB1
Clone[86CT4.4.4]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThis monoclonal antibody is generated from mice immunized with a recombinant protein human TBB1. This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.
Immunogenn/a
Other Names[Tubulin beta-1 chain; TUBB1]
Gene, Accession #[TUBB1], Gene ID: 81027, NCBI: NP_110400.1, UniProt: Q9H4B7
Catalog #MBS9200512
Price$165, $370
Order / More InfoTBB1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesStudy of 18 functional hemostatic polymorphisms in mucocutaneous bleeding disorders. Anton AI, et al. Ann Hematol, 2010 Nov. PMID 20532885. Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of beta-tubulin at Cys 12 and suppression of microtubule dynamics. Xu W, et al. Mol Cancer Ther, 2009 Dec. PMID 19996274. Genotype-phenotype relationship for six common polymorphisms in genes affecting platelet function from 286 healthy subjects and 160 patients with mucocutaneous bleeding of unknown cause. Martinez C, et al. Br J Haematol, 2009 Jun. PMID 19388931. TUBB1 Q43P polymorphism does not protect against acute coronary syndrome and premature myocardial infarction. Navarro-Nunez L, et al. Thromb Haemost, 2008 Dec. PMID 19132255. Roles of beta-tubulin residues Ala428 and Thr429 in microtubule formation in vivo. Joe PA, et al. J Biol Chem, 2009 Feb 13. PMID 19074767.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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