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Antigenic Specificity | Mouse Irak4 (C-term), 422-449 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Irak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-449 amino acids from the C-terminal region of mouse Irak4. Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity). |
Immunogen | n/a |
Other Names | [Interleukin-1 receptor-associated kinase 4; IRAK-4; Irak4] |
Gene, Accession # | [Irak4], Gene ID: 266632, NCBI: NP_084202.2, UniProt: Q8R4K2 |
Catalog # | MBS9213464 |
Price | $165, $370 |
Order / More Info | Mouse Irak4 (C-term), 422-449 Antibody from MYBIOSOURCE INC. |
Product Specific References | Erdman, L.K., et al. J. Immunol. 183(10):6452-6459(2009) Maekawa, Y., et al. Circulation 120(14):1401-1414(2009) Bauernfeind, F.G., et al. J. Immunol. 183(2):787-791(2009) Staschke, K.A., et al. J. Immunol. 183(1):568-577(2009) Koziczak-Holbro, M., et al. Arthritis Rheum. 60(6):1661-1671(2009) |