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Antigenic Specificity | Human CHEK2 / CHK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: synthetic peptide corresponding to amino acids near the amino terminus of human Chk2. CHK2 is a serine/threonine kinase in the CDS subfamily that is activated in response to DNA damage and may regulate cell cycle arrest. It is the human homolog of RAD53 in S. cerevisiae and CDS1 in S. pombe. The protein has a FHA domain, which means it is located in the nucleus. Its kinase activity is up regulated by autophosphorylation in response to DNA damage and to replication blocks. |
Immunogen | Immunogen Description: A synthetic peptide corresponding to amino acids near the amino terminus of human Chk2. |
Other Names | [CHEK2 / CHK2 (N-Terminus) IHC-plus; CHEK2; BA444G7; Cds1 homolog; Checkpoint kinase 2; Checkpoint-like protein CHK2; CHK2 checkpoint homolog; CHK2; HCds1; LFS2; RAD53; Rad53 homolog; HCHK2; HuCds1; PP1425; Human CHEK2; CHK2], [CHK2] |
Gene, Accession # | [CHEK2], Gene ID: 11200, NCBI: NP_009125.1, UniProt: O96017 |
Catalog # | MBS241264 |
Price | $530 |
Order / More Info | Human CHEK2 / CHK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |