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Antigenic Specificity | Human B-cell Activating Factor |
Clone | [PH4C7AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG3 |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: Binds to tnfrsf13b/taci and tnfrsf17/bcma. tnfsf13/april binds to the same 2 receptors, together, they form a 2 ligands -2 receptors pathway involved in the stimulation of b- and t-cell function and the regulation of humoral immunity. A third b-cell specific baff-receptor (baffr/br3) promotes the survival of mature b-cells and the b-cell response. B Lymphocyte Stimulator functions as a potent B-cell growth factor in costimulation assays. Administration of BAFF Human recombinant to mice disrupts splenic B-cell and T-cell zones and results in elevated levels of serum immunoglobulin. |
Immunogen | Immunogen: Anti-human BAFF mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with Recombinant human BAFF amino acids 134-285 purified from E Coli. |
Other Names | [BAFF; B-cell Activating Factor, Mouse Human; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; TNFSF13B], [TNFSF13B; TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; BLyS; TALL-1] |
Gene, Accession # | [BAFF], Gene ID: 10673, NCBI: NP_001139117.1 |
Catalog # | MBS140214 |
Price | $140, $205, $505 |
Order / More Info | Human B-cell Activating Factor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |